Prolonged Detection of Zika Virus in Vaginal Secretions and Whole Blood

نویسندگان

  • Kristy O. Murray
  • Rodion Gorchakov
  • Anna R. Carlson
  • Rebecca Berry
  • Lilin Lai
  • Muktha Natrajan
  • Melissa N. Garcia
  • Armando Correa
  • Shital M. Patel
  • Kjersti Aagaard
  • Mark J. Mulligan
چکیده

Infection with Zika virus is an emerging public health crisis. We observed prolonged detection of virus RNA in vaginal mucosal swab specimens and whole blood for a US traveler with acute Zika virus infection who had visited Honduras. These findings advance understanding of Zika virus infection and provide data for additional testing strategies.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Infectious Zika virus in vaginal secretions from an HIV-infected woman, France, August 2016

A woman with controlled HIV infection developed in late August 2016 a pruritic rash with fever and conjunctival hyperaemia after a trip to the French Caribbean islands. On day 3 after symptom onset, Zika virus RNA was detected in plasma, urine and vaginal samples with respective viral loads of 3.8, 6.1 and 5.3 log copies/mL. Notably, we demonstrated the presence of infectious Zika virus particl...

متن کامل

Zika virus preferentially replicates in the female reproductive tract after vaginal inoculation of rhesus macaques

Zika virus (ZIKV) is a mosquito-transmitted virus that can cause severe defects in an infected fetus. ZIKV is also transmitted by sexual contact, although the relative importance of sexual transmission is unclear. To better understand the role of sexual transmission in ZIKV pathogenesis, a nonhuman primate (NHP) model of vaginal transmission was developed. ZIKV was readily transmitted to mature...

متن کامل

Zika Virus Infection and Prolonged Viremia in Whole-Blood Specimens

We tested whole-blood and plasma samples from immunocompetent patients who had had benign Zika virus infections and found that Zika virus RNA persisted in whole blood substantially longer than in plasma. This finding may have implications for diagnosis of acute symptomatic and asymptomatic infections and for testing of blood donations.

متن کامل

مروری بر ویروسِ زیکا، آربو ویروسِ بازپدید: مقاله مروری

Before the recent outbreaks of Zika virus, few people have ever heard of its name. Even virologists had paid little attention to this member of the Flaviviridae family. Hence, up to January 2016, only 269 articles about Zika virus had been indexed in PubMed compared to the 9187 articles related to dengue virus. However, declaration of the World health organization (WHO) about the global Zika vi...

متن کامل

مروری بر بیماری زیکا: تهدیدی تازه برای بهداشت جامعه

Introduction: Zika virus was identified in Uganda in the Zika Forest in 1947. It is a tropical disease transmitted by mosquito which is similar to Dengune virus, the western Nile virus and yellow fever. While the virus does not cause the illness in mosquitoes, feeding mosquitoes from the blood of the patients transmit virus to the healthy subjects. The prevalence of the virus was limited to Afr...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:

دوره 23  شماره 

صفحات  -

تاریخ انتشار 2017